Bene Gesserit Sisterhood
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The Bene Gesserit Sisterhood is an ancient order of spies, advisors, and truthsayers that manipulates the Imperium from the shadows. Theirs is the hand that seeks to steer the very evolution of humanity.
Lore
A secretive and feared sisterhood that utilizes genetic experimentation, via selective breeding, to directly influence the politics of the Imperium. Their overall goal is the eventual creation of their chosen one, the Kwisatz Haderach.
In-Game
Lady Jessica is a member of this order, and in this Alternate Timeline, gives birth to a daughter, Ariste Atreides, instead of Paul Atreides. As a result of her obedience to the Sisterhood, she is trained as a truthsayer and foils Dr. Yueh's plan, allowing the Atreides to survive the ambush during the Siege of Arrakeen.
Players also encounter Jocasta Cleo, a Sister on the run. She served as part of the Missionara Protectiva, a branch of the Sisterhood tasked with intentionally seeding prophecies among world populations to control them.