Poison

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A Muad'Dib as shown in Shigawire reel 6

There will be poison in Dune: Awakening[1][2], although it's extent and usability is not known yet, it will work on the Muad'Dib's that roam the desert[1]; suspected there is likely a Mentat Ability or passive that somehow ties into this poison mechanic via its symbol on the skill tree, but there is no confirmation.

References