THIS PAGE CONTAINS STORY SPOILERS

Lore Changes Book/Movie to Game

Paul Atreides is never born. Instead, Lady Jessica follows the Bene Gesserit's orders and has a girl child to get closer to a kwisatz haderach.^[1]
This daughter's name is Ariste Atreides.
Dr. Yueh is exposed before his betrayal as Jessica was trained as a truthsayer (as she remained loyal to the Bene Gesserit by giving birth to Ariste^[2]), allowing Duke Leto Atredies and his house to survive.^[1]
To protect spice production on Arrakis, the Emperor deploys his Sardaukar^[1]
Arrakis erupts into a war of assassins.^[1] This war is sanctioned by the Emperor as long as the war remains contained. However, spice must flow.^[3]
The Fremen are missing, presumed exterminated by Imperial propaganda and unreliable narrator^[1]^[4]^[5]